I was thinking about 2 Cor 12 and Paul's thorn. There is a lot of speculation about what that thorn is, me personally I don't know. But these verses say to me about Paul's struggle and his humaness. A man chosen by God with a clear mission and yet he has his own personal struggle. I find that really encouraging that God has a clear purpose for each one of us, even on the days when stuff seriously gets on top of us, our own personal struggle. God still has a calling on our life.